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10.1093/ckj/sfw020

http://scihub22266oqcxt.onion/10.1093/ckj/sfw020
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suck abstract from ncbi


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pmid27274824
      Clin+Kidney+J 2016 ; 9 (3 ): 403-7
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  • Kidney transplant outcomes in familial C3 glomerulopathy #MMPMID27274824
  • Wong L ; Moran S ; Lavin PJ ; Dorman AM ; Conlon PJ
  • Clin Kidney J 2016[Jun]; 9 (3 ): 403-7 PMID27274824 show ga
  • C3 glomerulopathy, a newly designated entity, is characterized by glomerular disease associated with dysregulation of the alternative complement pathway and is a rare cause of end-stage kidney disease. Overall disease characteristics that include clinical presentation, laboratory assessment, histopathology and genetic background have only been unravelled in recent years and have led to the development of anti-complement therapies targeting different levels of the alternative pathway. We describe the long-term outcomes following kidney transplantation in an Irish family with familial C3 glomerulopathy due to a hybrid CFHR3-1 gene.
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