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10.1007/s40139-015-0069-z http://scihub22266oqcxt.onion/10.1007/s40139-015-0069-z C4477536!4477536!26120499     free     free     free Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26120499.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Curr+Pathobiol+Rep 2015 ; 3 (1): 67-79 Nephropedia Template TP {{tp|p=26120499|t=2015. Kidney Regeneration: Lessons from Development |pdf=|usr=}}{{26120499}} gab.com Text Kidney Regeneration: Lessons from Development JO: Curr Pathobiol Rep http://www.kidney.de/pget.php?&tw=1&pmid=26120499 #FOAvip A number of genes involved in kidney development are reactivated in the adult after acute kidney injury (AKI). This has led to the belief that tissue repair mechanisms recapitulate pathways involved in embryonic development after AKI. We will discuss evidence to support this hypothesis by comparing the mechanisms of development with common pathways known to regulate post-AKI repair, or that we identified as cell-specific candidates based on public datasets from recent AKI translational profiling studies. We will argue that while many of these developmental pathways are reactivated after AKI, this is not associated with general cellular reprogramming to an embryonic state. We will show that reactivation of these developmental genes is often associated with expression in cells that are not normally involved in mediating parallel responses in the embryo, and that depending on the cellular context, these responses can have beneficial or detrimental effects on injury and repair after AKI. Twit Text FOAVip Kidney Regeneration: Lessons from Development ????Curr Pathobiol Rep http://www.kidney.de/pget.php?&tw=1&pmid=26120499 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26120499 #FOAvip English Wikipedia <ref>{{Cite pmid|26120499}}</ref> Kidney Regeneration: Lessons from Development #MMPMID26120499 Chiba T; Hukriede N; de Caestecker MP Curr Pathobiol Rep 2015[Mar]; 3 (1): 67-79 PMID26120499show ga A number of genes involved in kidney development are reactivated in the adult after acute kidney injury (AKI). This has led to the belief that tissue repair mechanisms recapitulate pathways involved in embryonic development after AKI. We will discuss evidence to support this hypothesis by comparing the mechanisms of development with common pathways known to regulate post-AKI repair, or that we identified as cell-specific candidates based on public datasets from recent AKI translational profiling studies. We will argue that while many of these developmental pathways are reactivated after AKI, this is not associated with general cellular reprogramming to an embryonic state. We will show that reactivation of these developmental genes is often associated with expression in cells that are not normally involved in mediating parallel responses in the embryo, and that depending on the cellular context, these responses can have beneficial or detrimental effects on injury and repair after AKI. äKidney Regeneration: Lessons from Development (epmc).pdf DeepDyve Pubget Overpricing