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10.1016/j.molmed.2017.01.001 http://scihub22266oqcxt.onion/10.1016/j.molmed.2017.01.001 C5442988!5442988 !28188103     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=28188103 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215       Trends+Mol+Med 2017 ; 23 (3 ): 246-263 Nephropedia Template TP {{tp|p=28188103 |t=2017. Kidney Organoids: A Translational Journey |pdf=|usr=}}{{28188103 }} gab.com Text Kidney Organoids: A Translational Journey JO: Trends Mol Med http://www.kidney.de/pget.php?&tw=1&pmid=28188103 #FOAvip Human pluripotent stem cells (hPSCs) are attractive sources for regenerative medicine and disease modeling in vitro. Directed hPSC differentiation approaches have derived from knowledge of cell development in vivo rather than from stochastic cell differentiation. Moreover, there has been great success in the generation of 3D organ-buds termed 'organoids' from hPSCs; these consist of a variety of cell types in vitro that mimic organs in vivo. The organoid bears great potential in the study of human diseases in vitro, especially when combined with CRISPR/Cas9-based genome-editing. We summarize the current literature describing organoid studies with a special focus on kidney organoids, and discuss goals and future opportunities for organoid-based studies. Twit Text FOAVip Kidney Organoids: A Translational Journey ????Trends Mol Med http://www.kidney.de/pget.php?&tw=1&pmid=28188103 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28188103 #FOAvip English Wikipedia <ref>{{Cite pmid|28188103 }}</ref> Kidney Organoids: A Translational Journey #MMPMID28188103 Morizane R ; Bonventre JV Trends Mol Med 2017[Mar]; 23 (3 ): 246-263 PMID28188103 show ga Human pluripotent stem cells (hPSCs) are attractive sources for regenerative medicine and disease modeling in vitro. Directed hPSC differentiation approaches have derived from knowledge of cell development in vivo rather than from stochastic cell differentiation. Moreover, there has been great success in the generation of 3D organ-buds termed 'organoids' from hPSCs; these consist of a variety of cell types in vitro that mimic organs in vivo. The organoid bears great potential in the study of human diseases in vitro, especially when combined with CRISPR/Cas9-based genome-editing. We summarize the current literature describing organoid studies with a special focus on kidney organoids, and discuss goals and future opportunities for organoid-based studies. |Animals [MESH] |Cell Differentiation [MESH] |Humans [MESH] |Kidney/*cytology/physiology [MESH] |Nephrons/*cytology/physiology [MESH] |Organoids/*cytology/metabolism [MESH] |Pluripotent Stem Cells/*cytology/pathology [MESH] |Regeneration [MESH] |Regenerative Medicine/methods [MESH]Kidney Organoids: A Translational Journey (epmc).pdf DeepDyve Pubget Overpricing