Front Pediatr
2018[]; 6
(?): 198
PMID30042935
show ga
Kawasaki disease (KD) is an acute-onset systemic vasculitis of medium-sized
vessels that mostly affects infants and toddlers. Globally, it is the most common
form of childhood primary vasculitis. Delayed diagnosis and treatment results in
coronary artery aneurysms in up to 25% of all affected individuals. Thus, KD is
the most common acquired heart disease in developed countries. Here, the current
understanding of clinical presentations, pathophysiological concepts,
disease-associated complications, and available pharmaceutical treatment is
provided and discussed in the context of available literature.