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10.3892/mmr.2017.6117 http://scihub22266oqcxt.onion/10.3892/mmr.2017.6117 C5367367!5367367 !28098889     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=28098889 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\28098889 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Mol+Med+Rep 2017 ; 15 (3 ): 1071-1078 Nephropedia Template TP {{tp|p=28098889 |t=2017. IsomiR expression patterns in canonical and Dicer?independent microRNAs |pdf=|usr=}}{{28098889 }} gab.com Text IsomiR expression patterns in canonical and Dicer independent microRNAs JO: Mol Med Rep http://www.kidney.de/pget.php?&tw=1&pmid=28098889 #FOAvip Multiple microRNA (miRNA) variants, known as isomiRs, are extensively distributed in miRNA loci and predominantly derive from the alternative cleavage of Drosha/Dicer and 3'addition events. The present study aimed to investigate the expression patterns of multiple isomiRs in typical miRNA and Dicer?independent miRNA loci by conducting evolutionary and expression analysis using public datasets. Although different miRNA maturation processes exist, multiple isomiRs can be detected by similar expression distributions. However, isomiR expression in Dicer?independent miRNA loci tends to be at a moderate level, particularly for random distribution in the ends that are split by Dicer in the typical miRNA loci. Compared with the mature miRNA locus (dominant miRNA locus), the non?dominant miRNA locus indicates an expression distribution similar to that of the Dicer?independent miRNA locus. These results increase the understanding of multiple isomiRs in the progression of diseases. Twit Text FOAVip IsomiR expression patterns in canonical and Dicer independent microRNAs ????Mol Med Rep http://www.kidney.de/pget.php?&tw=1&pmid=28098889 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28098889 #FOAvip English Wikipedia <ref>{{Cite pmid|28098889 }}</ref> IsomiR expression patterns in canonical and Dicer?independent microRNAs #MMPMID28098889 Liang T ; Yu J ; Liu C ; Guo L Mol Med Rep 2017[Mar]; 15 (3 ): 1071-1078 PMID28098889 show ga Multiple microRNA (miRNA) variants, known as isomiRs, are extensively distributed in miRNA loci and predominantly derive from the alternative cleavage of Drosha/Dicer and 3'addition events. The present study aimed to investigate the expression patterns of multiple isomiRs in typical miRNA and Dicer?independent miRNA loci by conducting evolutionary and expression analysis using public datasets. Although different miRNA maturation processes exist, multiple isomiRs can be detected by similar expression distributions. However, isomiR expression in Dicer?independent miRNA loci tends to be at a moderate level, particularly for random distribution in the ends that are split by Dicer in the typical miRNA loci. Compared with the mature miRNA locus (dominant miRNA locus), the non?dominant miRNA locus indicates an expression distribution similar to that of the Dicer?independent miRNA locus. These results increase the understanding of multiple isomiRs in the progression of diseases. |*Transcriptome [MESH] |Databases, Nucleic Acid [MESH] |Evolution, Molecular [MESH] |Gene Expression Profiling [MESH] |Gene Expression Regulation [MESH] |Genetic Loci [MESH] |Humans [MESH] |MicroRNAs/*genetics [MESH]IsomiR expression patterns in canonical and Dicer?independent microRNA(epmc).pdf DeepDyve Pubget Overpricing