Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1038/nature15709 http://scihub22266oqcxt.onion/10.1038/nature15709 C4890463!4890463 !26503040     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26503040 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Nature 2015 ; 527 (7576 ): 59-63 Nephropedia Template TP {{tp|p=26503040 |t=2015. Ion channels enable electrical communication in bacterial communities |pdf=|usr=}}{{26503040 }} gab.com Text Ion channels enable electrical communication in bacterial communities JO: Nature http://www.kidney.de/pget.php?&tw=1&pmid=26503040 #FOAvip The study of bacterial ion channels has provided fundamental insights into the structural basis of neuronal signalling; however, the native role of ion channels in bacteria has remained elusive. Here we show that ion channels conduct long-range electrical signals within bacterial biofilm communities through spatially propagating waves of potassium. These waves result from a positive feedback loop, in which a metabolic trigger induces release of intracellular potassium, which in turn depolarizes neighbouring cells. Propagating through the biofilm, this wave of depolarization coordinates metabolic states among cells in the interior and periphery of the biofilm. Deletion of the potassium channel abolishes this response. As predicted by a mathematical model, we further show that spatial propagation can be hindered by specific genetic perturbations to potassium channel gating. Together, these results demonstrate a function for ion channels in bacterial biofilms, and provide a prokaryotic paradigm for active, long-range electrical signalling in cellular communities. Twit Text FOAVip Ion channels enable electrical communication in bacterial communities ????Nature http://www.kidney.de/pget.php?&tw=1&pmid=26503040 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26503040 #FOAvip English Wikipedia <ref>{{Cite pmid|26503040 }}</ref> Ion channels enable electrical communication in bacterial communities #MMPMID26503040 Prindle A ; Liu J ; Asally M ; Ly S ; Garcia-Ojalvo J ; Süel GM Nature 2015[Nov]; 527 (7576 ): 59-63 PMID26503040 show ga The study of bacterial ion channels has provided fundamental insights into the structural basis of neuronal signalling; however, the native role of ion channels in bacteria has remained elusive. Here we show that ion channels conduct long-range electrical signals within bacterial biofilm communities through spatially propagating waves of potassium. These waves result from a positive feedback loop, in which a metabolic trigger induces release of intracellular potassium, which in turn depolarizes neighbouring cells. Propagating through the biofilm, this wave of depolarization coordinates metabolic states among cells in the interior and periphery of the biofilm. Deletion of the potassium channel abolishes this response. As predicted by a mathematical model, we further show that spatial propagation can be hindered by specific genetic perturbations to potassium channel gating. Together, these results demonstrate a function for ion channels in bacterial biofilms, and provide a prokaryotic paradigm for active, long-range electrical signalling in cellular communities. |*Electric Conductivity [MESH] |Bacillus subtilis/*cytology/growth & development/*metabolism [MESH] |Biofilms/*growth & development [MESH] |Feedback, Physiological [MESH] |Ion Channel Gating [MESH] |Membrane Potentials [MESH] |Models, Biological [MESH] |Potassium Channels/*metabolism [MESH] |Potassium/metabolism [MESH]Ion channels enable electrical communication in bacterial communities (epmc).pdf DeepDyve Pubget Overpricing