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2018 ; 12
(1
): 205-210
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Involvement of Tsukushi in diverse developmental processes
#MMPMID29352451
Ahmad SAI
; Anam MB
; Ito N
; Ohta K
J Cell Commun Signal
2018[Mar]; 12
(1
): 205-210
PMID29352451
show ga
Tsukushi (TSK) is a small signaling molecule which takes part in different
developmental processes of multiple vertebrate organisms. The diverse activity of
TSK depends on its ability to bind various intermediate molecules from different
major signaling pathways. Interactions of TSK with BMP, FGF, TGF-? and Wnt
pathways have already been confirmed. In this review, we will introduce the
latest information regarding the involvement of TSK in developmental events. We
suggest a fine tuning role for TSK in multiple signaling cascades. Also, we
recommend further studies on the developmental role of TSK to fully reveal its
potential.