Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=26417383
&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215
Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26417383
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Nat+Photonics
2015 ; 9
(9
): 572-576
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Intracellular microlasers
#MMPMID26417383
Humar M
; Yun SH
Nat Photonics
2015[Sep]; 9
(9
): 572-576
PMID26417383
show ga
Optical microresonators(1) which confine light within a small cavity are widely
exploited for various applications ranging from the realization of lasers(2) and
nonlinear devices(3, 4, 5) to biochemical and optomechanical sensing(6, 7, 8, 9,
10, 11). Here we employ microresonators and suitable optical gain materials
inside biological cells to demonstrate various optical functions in vitro
including lasing. We explored two distinct types of microresonators: soft and
hard, that support whispering-gallery modes (WGM). Soft droplets formed by
injecting oil or using natural lipid droplets support intracellular laser action.
The laser spectra from oil-droplet microlasers can chart cytoplasmic internal
stress (~500 pN/?m(2)) and its dynamic fluctuations at a sensitivity of 20
pN/?m(2) (20 Pa). In a second form, WGMs within phagocytized polystyrene beads of
different sizes enable individual tagging of thousands of cells easily and, in
principle, a much larger number by multiplexing with different dyes.