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2013 ; 2013
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Into the wild world of eosinophilic granuloma
#MMPMID24252836
Dhull AK
; Aggarwal S
; Kaushal V
; Singh S
BMJ Case Rep
2013[Nov]; 2013
(ä): ä PMID24252836
show ga
Langerhans cell histiocytosis (LCH) is a group of relatively rare disease
processes of reticuloendothelial system with an abnormal proliferation of
Langerhans cells or their precursors. A wide spectrum of treatment modalities is
available for LCH which includes surgery, curettage, steroids, radiation, various
chemotherapy regimens, either in combination or alone have so far been adopted.
There are several case reports of eosinophilic granuloma but for recurrent cases
very few have discussed on treatment of LCH in adults. We report a case of a
21-year-old man presented with eosinophilic granuloma with recurrence of the
lesions after 6 years of the initial treatment. Patient was treated with
combination chemotherapy with three weekly CHOP regimen and the patient is
disease free after 6 months of follow-up. Contrary to other reports, this case
demonstrates that a good response with standard therapy is possible.
|Antineoplastic Combined Chemotherapy Protocols/therapeutic use
[MESH]