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10.1007/s00441-012-1468-7 http://scihub22266oqcxt.onion/10.1007/s00441-012-1468-7 C4806557!4806557 !22864981     free     free     free Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\22864981 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Cell+Tissue+Res 2012 ; 350 (2 ): 199-213 Nephropedia Template TP {{tp|p=22864981 |t=2012. Interstitial cells in the primate gastrointestinal tract |pdf=|usr=}}{{22864981 }} gab.com Text Interstitial cells in the primate gastrointestinal tract JO: Cell Tissue Res http://www.kidney.de/pget.php?&tw=1&pmid=22864981 #FOAvip Kit immunohistochemistry and confocal reconstructions have provided detailed 3-dimensional images of ICC networks throughout the gastrointestinal (GI) tract. Morphological criteria have been used to establish that different classes of ICC exist within the GI tract and physiological studies have shown that these classes have distinct physiological roles in GI motility. Structural studies have focused predominately on rodent models and less information is available on whether similar classes of ICC exist within the GI tracts of humans or non-human primates. Using Kit immunohistochemistry and confocal imaging, we examined the 3-dimensional structure of ICC throughout the GI tract of cynomolgus monkeys. Whole or flat mounts and cryostat sections were used to examine ICC networks in the lower esophageal sphincter (LES), stomach, small intestine and colon. Anti-histamine antibodies were used to distinguish ICC from mast cells in the lamina propria. Kit labeling identified complex networks of ICC populations throughout the non-human primate GI tract that have structural characteristics similar to that described for ICC populations in rodent models. ICC-MY formed anastomosing networks in the myenteric plexus region. ICC-IM were interposed between smooth muscle cells in the stomach and colon and were concentrated within the deep muscular plexus (ICC-DMP) of the intestine. ICC-SEP were found in septal regions of the antrum that separated circular muscle bundles. Spindle-shaped histamine(+) mast cells were found in the lamina propria throughout the GI tract. Since similar sub-populations of ICC exist within the GI tract of primates and rodents and the use of rodents to study the functional roles of different classes of ICC is warranted. Twit Text FOAVip Interstitial cells in the primate gastrointestinal tract ????Cell Tissue Res http://www.kidney.de/pget.php?&tw=1&pmid=22864981 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=22864981 #FOAvip English Wikipedia <ref>{{Cite pmid|22864981 }}</ref> Interstitial cells in the primate gastrointestinal tract #MMPMID22864981 Blair PJ ; Bayguinov Y ; Sanders KM ; Ward SM Cell Tissue Res 2012[Nov]; 350 (2 ): 199-213 PMID22864981 show ga Kit immunohistochemistry and confocal reconstructions have provided detailed 3-dimensional images of ICC networks throughout the gastrointestinal (GI) tract. Morphological criteria have been used to establish that different classes of ICC exist within the GI tract and physiological studies have shown that these classes have distinct physiological roles in GI motility. Structural studies have focused predominately on rodent models and less information is available on whether similar classes of ICC exist within the GI tracts of humans or non-human primates. Using Kit immunohistochemistry and confocal imaging, we examined the 3-dimensional structure of ICC throughout the GI tract of cynomolgus monkeys. Whole or flat mounts and cryostat sections were used to examine ICC networks in the lower esophageal sphincter (LES), stomach, small intestine and colon. Anti-histamine antibodies were used to distinguish ICC from mast cells in the lamina propria. Kit labeling identified complex networks of ICC populations throughout the non-human primate GI tract that have structural characteristics similar to that described for ICC populations in rodent models. ICC-MY formed anastomosing networks in the myenteric plexus region. ICC-IM were interposed between smooth muscle cells in the stomach and colon and were concentrated within the deep muscular plexus (ICC-DMP) of the intestine. ICC-SEP were found in septal regions of the antrum that separated circular muscle bundles. Spindle-shaped histamine(+) mast cells were found in the lamina propria throughout the GI tract. Since similar sub-populations of ICC exist within the GI tract of primates and rodents and the use of rodents to study the functional roles of different classes of ICC is warranted. |Animals [MESH] |Female [MESH] |Gastrointestinal Tract/*cytology/metabolism [MESH] |Humans [MESH] |Immunohistochemistry [MESH] |Interstitial Cells of Cajal/*cytology/metabolism [MESH] |Macaca fascicularis [MESH]Interstitial cells in the primate gastrointestinal tract (epmc).pdf DeepDyve Pubget Overpricing