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10.1016/j.coviro.2014.03.006

http://scihub22266oqcxt.onion/10.1016/j.coviro.2014.03.006
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suck abstract from ncbi


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pmid24713352
      Curr+Opin+Virol 2014 ; 6 (ä): 40-6
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  • Interferon-stimulated genes: roles in viral pathogenesis #MMPMID24713352
  • Schoggins JW
  • Curr Opin Virol 2014[Jun]; 6 (ä): 40-6 PMID24713352 show ga
  • Interferon-stimulated genes (ISGs) are critical for controlling virus infections. As new antiviral ISGs continue to be identified and characterized, their roles in viral pathogenesis are also being explored in more detail. Our current understanding of how ISGs impact viral pathogenesis comes largely from studies in knockout mice, with isolated examples from human clinical data. This review outlines recent developments on the contributions of various ISGs to viral disease outcomes in vivo.
  • |*Host-Pathogen Interactions/drug effects/genetics [MESH]
  • |Animals [MESH]
  • |Gene Expression Regulation/*drug effects [MESH]
  • |Humans [MESH]
  • |Interferons/metabolism/*pharmacology [MESH]
  • |Virus Diseases/*genetics/metabolism/*virology [MESH]


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