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2017 ; 8
(10
): ä Nephropedia Template TP
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Intercompartmental Piecewise Gene Transfer
#MMPMID28984842
Szafranski P
Genes (Basel)
2017[Oct]; 8
(10
): ä PMID28984842
show ga
Gene relocation from the residual genomes of organelles to the nuclear genome
still continues, although as a scaled down evolutionary phenomenon, limited in
occurrence mostly to protists (sensu lato) and land plants. During this process,
the structural integrity of transferred genes is usually preserved. However, the
relocation of mitochondrial genes that code for respiratory chain and ribosomal
proteins is sometimes associated with their fragmentation into two complementary
genes. Herein, this review compiles cases of piecewise gene transfer from the
mitochondria to the nucleus, and discusses hypothesized mechanistic links between
the fission and relocation of those genes.