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10.1146/annurev-micro-091014-104115 http://scihub22266oqcxt.onion/10.1146/annurev-micro-091014-104115 C4892173!4892173 !26488281     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26488281 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Annu+Rev+Microbiol 2015 ; 69 (ä): 445-61 Nephropedia Template TP {{tp|p=26488281 |t=2015. Interactions Between the Gastrointestinal Microbiome and Clostridium difficile |pdf=|usr=}}{{26488281 }} gab.com Text Interactions Between the Gastrointestinal Microbiome and Clostridium difficile JO: Annu Rev Microbiol http://www.kidney.de/pget.php?&tw=1&pmid=26488281 #FOAvip Antibiotics have significant and long-lasting effects on the intestinal microbiota and consequently reduce colonization resistance against pathogens, including Clostridium difficile. By altering the community structure of the gut microbiome, antibiotics alter the intestinal metabolome, which includes both host- and microbe-derived metabolites. The mechanisms by which antibiotics reduce colonization resistance against C. difficile are unknown yet important for development of preventative and therapeutic approaches against this pathogen. This review focuses on how antibiotics alter the structure of the gut microbiota and how this alters microbial metabolism in the intestine. Interactions between gut microbial products and C. difficile spore germination, growth, and toxin production are discussed. New bacterial therapies to restore changes in bacteria-driven intestinal metabolism following antibiotics will have important applications for treatment and prevention of C. difficile infection. Twit Text FOAVip Interactions Between the Gastrointestinal Microbiome and Clostridium difficile ????Annu Rev Microbiol http://www.kidney.de/pget.php?&tw=1&pmid=26488281 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26488281 #FOAvip English Wikipedia <ref>{{Cite pmid|26488281 }}</ref> Interactions Between the Gastrointestinal Microbiome and Clostridium difficile #MMPMID26488281 Theriot CM ; Young VB Annu Rev Microbiol 2015[]; 69 (ä): 445-61 PMID26488281 show ga Antibiotics have significant and long-lasting effects on the intestinal microbiota and consequently reduce colonization resistance against pathogens, including Clostridium difficile. By altering the community structure of the gut microbiome, antibiotics alter the intestinal metabolome, which includes both host- and microbe-derived metabolites. The mechanisms by which antibiotics reduce colonization resistance against C. difficile are unknown yet important for development of preventative and therapeutic approaches against this pathogen. This review focuses on how antibiotics alter the structure of the gut microbiota and how this alters microbial metabolism in the intestine. Interactions between gut microbial products and C. difficile spore germination, growth, and toxin production are discussed. New bacterial therapies to restore changes in bacteria-driven intestinal metabolism following antibiotics will have important applications for treatment and prevention of C. difficile infection. |*Gastrointestinal Microbiome/drug effects [MESH] |Animals [MESH] |Anti-Bacterial Agents/administration & dosage [MESH] |Clostridioides difficile/*metabolism [MESH] |Clostridium Infections/*microbiology [MESH] |Fermentation [MESH] |Humans [MESH] |Immune Evasion [MESH] |Microbial Interactions [MESH]Interactions Between the Gastrointestinal Microbiome and Clostridium d(epmc).pdf DeepDyve Pubget Overpricing