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10.3390/ijms19020485 http://scihub22266oqcxt.onion/10.3390/ijms19020485 C5855707!5855707!29415483     free     free     free Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\29415483.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Int+J+Mol+Sci 2018 ; 19 (2): ä Nephropedia Template TP {{tp|p=29415483|t=2018. Integrins in T Cell Physiology |pdf=|usr=}}{{29415483}} gab.com Text Integrins in T Cell Physiology JO: Int J Mol Sci http://www.kidney.de/pget.php?&tw=1&pmid=29415483 #FOAvip From the thymus to the peripheral lymph nodes, integrin-mediated interactions with neighbor cells and the extracellular matrix tune T cell behavior by organizing cytoskeletal remodeling and modulating receptor signaling. LFA-1 (?L?2 integrin) and VLA-4 (?4?1 integrin) play a key role throughout the T cell lifecycle from thymocyte differentiation to lymphocyte extravasation and finally play a fundamental role in organizing immune synapse, providing an essential costimulatory signal for the T cell receptor. Apart from tuning T cell signaling, integrins also contribute to homing to specific target organs as exemplified by the importance of ?4?7 in maintaining the gut immune system. However, apart from those well-characterized examples, the physiological significance of the other integrin dimers expressed by T cells is far less understood. Thus, integrin-mediated cell-to-cell and cell-to-matrix interactions during the T cell lifespan still represent an open field of research. Twit Text FOAVip Integrins in T Cell Physiology ????Int J Mol Sci http://www.kidney.de/pget.php?&tw=1&pmid=29415483 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29415483 #FOAvip English Wikipedia <ref>{{Cite pmid|29415483}}</ref> Integrins in T Cell Physiology #MMPMID29415483 Bertoni A; Alabiso O; Galetto AS; Baldanzi G Int J Mol Sci 2018[Feb]; 19 (2): ä PMID29415483show ga From the thymus to the peripheral lymph nodes, integrin-mediated interactions with neighbor cells and the extracellular matrix tune T cell behavior by organizing cytoskeletal remodeling and modulating receptor signaling. LFA-1 (?L?2 integrin) and VLA-4 (?4?1 integrin) play a key role throughout the T cell lifecycle from thymocyte differentiation to lymphocyte extravasation and finally play a fundamental role in organizing immune synapse, providing an essential costimulatory signal for the T cell receptor. Apart from tuning T cell signaling, integrins also contribute to homing to specific target organs as exemplified by the importance of ?4?7 in maintaining the gut immune system. However, apart from those well-characterized examples, the physiological significance of the other integrin dimers expressed by T cells is far less understood. Thus, integrin-mediated cell-to-cell and cell-to-matrix interactions during the T cell lifespan still represent an open field of research. äIntegrins in T Cell Physiology (epmc).pdf DeepDyve Pubget Overpricing