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2015 ; 135
(3
): 673-678
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Innate lymphoid cells in the skin
#MMPMID25339380
Kim BS
J Invest Dermatol
2015[Mar]; 135
(3
): 673-678
PMID25339380
show ga
Innate lymphoid cells (ILCs) are part of a heterogeneous family of innate immune
cells with newly identified roles in mediating immunity, tissue homeostasis, and
pathologic inflammation. Here, we review recent studies delineating the roles of
ILCs in the pathogenesis of multiple inflammatory skin disorders and their unique
effector functions. Finally, we address how these studies have informed our
understanding of the regulation of ILCs and the therapeutic potential of
targeting these cells in the context of skin inflammation.