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10.1038/ni.3244 http://scihub22266oqcxt.onion/10.1038/ni.3244 C4575627!4575627 !26322482     free     free     free Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26322482 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Nat+Immunol 2015 ; 16 (10 ): 1051-9 Nephropedia Template TP {{tp|p=26322482 |t=2015. Innate immunological function of TH2 cells in vivo |pdf=|usr=}}{{26322482 }} gab.com Text Innate immunological function of TH2 cells in vivo JO: Nat Immunol http://www.kidney.de/pget.php?&tw=1&pmid=26322482 #FOAvip Type 2 helper T cells (TH2 cells) produce interleukin 13 (IL-13) when stimulated by papain or house dust mite extract (HDM) and induce eosinophilic inflammation. This innate response is dependent on IL-33 but not T cell antigen receptors (TCRs). While type 2 innate lymphoid cells (ILC2 cells) are the dominant innate producers of IL-13 in naive mice, we found here that helminth-infected mice had more TH2 cells compared to uninfected mice, and thes e cells became major mediators of innate type 2 responses. TH2 cells made important contributions to HDM-induced antigen-nonspecific eosinophilic inflammation and protected mice recovering from infection with Ascaris suum against subsequent infection with the phylogenetically distant nematode Nippostrongylus brasiliensis. Our findings reveal a previously unappreciated role for effector TH2 cells during TCR-independent innate-like immune responses. Twit Text FOAVip Innate immunological function of TH2 cells in vivo ????Nat Immunol http://www.kidney.de/pget.php?&tw=1&pmid=26322482 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26322482 #FOAvip English Wikipedia <ref>{{Cite pmid|26322482 }}</ref> Innate immunological function of TH2 cells in vivo #MMPMID26322482 Guo L ; Huang Y ; Chen X ; Hu-Li J ; Urban JF Jr ; Paul WE Nat Immunol 2015[Oct]; 16 (10 ): 1051-9 PMID26322482 show ga Type 2 helper T cells (TH2 cells) produce interleukin 13 (IL-13) when stimulated by papain or house dust mite extract (HDM) and induce eosinophilic inflammation. This innate response is dependent on IL-33 but not T cell antigen receptors (TCRs). While type 2 innate lymphoid cells (ILC2 cells) are the dominant innate producers of IL-13 in naive mice, we found here that helminth-infected mice had more TH2 cells compared to uninfected mice, and thes e cells became major mediators of innate type 2 responses. TH2 cells made important contributions to HDM-induced antigen-nonspecific eosinophilic inflammation and protected mice recovering from infection with Ascaris suum against subsequent infection with the phylogenetically distant nematode Nippostrongylus brasiliensis. Our findings reveal a previously unappreciated role for effector TH2 cells during TCR-independent innate-like immune responses. |*Immunity, Innate [MESH] |Animals [MESH] |Flow Cytometry [MESH] |Helminthiasis/immunology [MESH] |Helminths/immunology [MESH] |Lung/cytology/immunology [MESH] |Lymphocytes/immunology [MESH] |Mice [MESH] |Polymerase Chain Reaction [MESH]Innate immunological function of TH2 cells in vivo (epmc).pdf DeepDyve Pubget Overpricing