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10.1038/s41590-018-0064-8

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C6027646!6027646!29507356
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suck abstract from ncbi


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pmid29507356      Nat+Immunol 2018 ; 19 (4): 327-41
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  • Innate immune responses to trauma #MMPMID29507356
  • Huber-Lang M; Lambris JD; Ward PA
  • Nat Immunol 2018[Apr]; 19 (4): 327-41 PMID29507356show ga
  • Trauma can affect any individual at any location and at any time over a lifespan. The disruption of macrobarriers and microbarriers induces instant activation of innate immunity. The subsequent complex response, designed to limit further damage and induce healing, also represents a major driver of complications and fatal outcome after injury. This Review aims to provide basic concepts about the posttraumatic response and is focused on the interactive events of innate immunity at frequent sites of injury: the endothelium at large, and sites within the lungs, inside and outside the brain and at the gut barrier.
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