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2015 ; 6
(2
): 101-11
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Injectable Coformulations in Diabetology
#MMPMID25801349
Kalra S
; Gupta Y
Diabetes Ther
2015[Jun]; 6
(2
): 101-11
PMID25801349
show ga
Coformulations are a novel pharmaceutical development in diabetology. They are
composed of two medicinal products, both of which maintain their distinct
pharmacokinetic and pharmacodynamic properties. Currently available
coformulations include combinations of basal and rapid-acting insulin, and basal
and glucagon-like peptide 1 receptor agonists (GLP1RA). This review describes
three coformulations which are in advanced stages of development, or are approved
in certain markets. We discuss the basic and clinical pharmacology of these
drugs, while describing clinical usage of the commercially available insulin
degludec aspart (IDegAsp).