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10.1016/j.virusres.2015.02.003

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suck abstract from ncbi


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pmid25678267
      Virus+Res 2015 ; 209 (ä): 11-22
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  • Influenza virus activation of the interferon system #MMPMID25678267
  • Killip MJ ; Fodor E ; Randall RE
  • Virus Res 2015[Nov]; 209 (ä): 11-22 PMID25678267 show ga
  • The host interferon (IFN) response represents one of the first barriers that influenza viruses must surmount in order to establish an infection. Many advances have been made in recent years in understanding the interactions between influenza viruses and the interferon system. In this review, we summarise recent work regarding activation of the type I IFN response by influenza viruses, including attempts to identify the viral RNA responsible for IFN induction, the stage of the virus life cycle at which it is generated and the role of defective viruses in this process.
  • |*Host-Pathogen Interactions [MESH]
  • |*Immunity, Innate [MESH]
  • |Defective Viruses/immunology [MESH]
  • |Humans [MESH]
  • |Interferon Type I/*metabolism [MESH]


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