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10.1016/j.imlet.2014.04.004 http://scihub22266oqcxt.onion/10.1016/j.imlet.2014.04.004 C4401421!4401421 !24938525     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=24938525 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\24938525 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Immunol+Lett 2014 ; 161 (2 ): 231-5 Nephropedia Template TP {{tp|p=24938525 |t=2014. Inflammatory bowel disease |pdf=|usr=}}{{24938525 }} gab.com Text Inflammatory bowel disease JO: Immunol Lett http://www.kidney.de/pget.php?&tw=1&pmid=24938525 #FOAvip Inflammatory bowel diseases (IBD), including Crohn's disease (CD) and ulcerative colitis (UC), are chronic, relapsing inflammatory condition of the gastrointestinal tract. CD and UC have distinct pathologic and clinical characteristics and despite the extensive amount of research conducted over the past decades, their pathogenesis remains still poorly understood. So far, the accepted dogma is that IBD results from dysregulated mucosal immune response to environmental factors in genetical susceptible hosts. Various components are implicated in the pathogenesis of IBD, including genetic susceptibility, environmental and microbial factors, intestinal epithelial cells and components of innate and adaptive immune system. Given the complexity of IBD, several different animal models of IBD have been developed during the last years. Animal models are very important tools to study the involvement of various factors in the pathogenesis of IBD and, importantly, to test new therapeutic options. This review examines some of the key components that have been found to be closely associated to IBD and describe the distinct features of some of the most important IBD models. Twit Text FOAVip Inflammatory bowel disease ????Immunol Lett http://www.kidney.de/pget.php?&tw=1&pmid=24938525 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24938525 #FOAvip English Wikipedia <ref>{{Cite pmid|24938525 }}</ref> Inflammatory bowel disease #MMPMID24938525 Corridoni D ; Arseneau KO ; Cominelli F Immunol Lett 2014[Oct]; 161 (2 ): 231-5 PMID24938525 show ga Inflammatory bowel diseases (IBD), including Crohn's disease (CD) and ulcerative colitis (UC), are chronic, relapsing inflammatory condition of the gastrointestinal tract. CD and UC have distinct pathologic and clinical characteristics and despite the extensive amount of research conducted over the past decades, their pathogenesis remains still poorly understood. So far, the accepted dogma is that IBD results from dysregulated mucosal immune response to environmental factors in genetical susceptible hosts. Various components are implicated in the pathogenesis of IBD, including genetic susceptibility, environmental and microbial factors, intestinal epithelial cells and components of innate and adaptive immune system. Given the complexity of IBD, several different animal models of IBD have been developed during the last years. Animal models are very important tools to study the involvement of various factors in the pathogenesis of IBD and, importantly, to test new therapeutic options. This review examines some of the key components that have been found to be closely associated to IBD and describe the distinct features of some of the most important IBD models. |Animals [MESH] |Disease Models, Animal [MESH] |Humans [MESH]Inflammatory bowel disease (epmc).pdf DeepDyve Pubget Overpricing