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10.1093/neuonc/nou212 http://scihub22266oqcxt.onion/10.1093/neuonc/nou212 C4201077!4201077 !25190673     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=25190673 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\25190673 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Neuro+Oncol 2014 ; 16 (11 ): 1441-58 Nephropedia Template TP {{tp|p=25190673 |t=2014. Immunotherapy advances for glioblastoma |pdf=|usr=}}{{25190673 }} gab.com Text Immunotherapy advances for glioblastoma JO: Neuro Oncol http://www.kidney.de/pget.php?&tw=1&pmid=25190673 #FOAvip Survival for patients with glioblastoma, the most common high-grade primary CNS tumor, remains poor despite multiple therapeutic interventions including intensifying cytotoxic therapy, targeting dysregulated cell signaling pathways, and blocking angiogenesis. Exciting, durable clinical benefits have recently been demonstrated for a number of other challenging cancers using a variety of immunotherapeutic approaches. Much modern research confirms that the CNS is immunoactive rather than immunoprivileged. Preliminary results of clinical studies demonstrate that varied vaccine strategies have achieved encouraging evidence of clinical benefit for glioblastoma patients, although multiple variables will likely require systematic investigation before optimal outcomes are realized. Initial preclinical studies have also revealed promising results with other immunotherapies including cell-based approaches and immune checkpoint blockade. Clinical studies to evaluate a wide array of immune therapies for malignant glioma patients are being rapidly developed. Important considerations going forward include optimizing response assessment and identifiying correlative biomarkers for predict therapeutic benefit. Finally, the potential of complementary combinatorial immunotherapeutic regimens is highly exciting and warrants expedited investigation. Twit Text FOAVip Immunotherapy advances for glioblastoma ????Neuro Oncol http://www.kidney.de/pget.php?&tw=1&pmid=25190673 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25190673 #FOAvip English Wikipedia <ref>{{Cite pmid|25190673 }}</ref> Immunotherapy advances for glioblastoma #MMPMID25190673 Reardon DA ; Freeman G ; Wu C ; Chiocca EA ; Wucherpfennig KW ; Wen PY ; Fritsch EF ; Curry WT Jr ; Sampson JH ; Dranoff G Neuro Oncol 2014[Nov]; 16 (11 ): 1441-58 PMID25190673 show ga Survival for patients with glioblastoma, the most common high-grade primary CNS tumor, remains poor despite multiple therapeutic interventions including intensifying cytotoxic therapy, targeting dysregulated cell signaling pathways, and blocking angiogenesis. Exciting, durable clinical benefits have recently been demonstrated for a number of other challenging cancers using a variety of immunotherapeutic approaches. Much modern research confirms that the CNS is immunoactive rather than immunoprivileged. Preliminary results of clinical studies demonstrate that varied vaccine strategies have achieved encouraging evidence of clinical benefit for glioblastoma patients, although multiple variables will likely require systematic investigation before optimal outcomes are realized. Initial preclinical studies have also revealed promising results with other immunotherapies including cell-based approaches and immune checkpoint blockade. Clinical studies to evaluate a wide array of immune therapies for malignant glioma patients are being rapidly developed. Important considerations going forward include optimizing response assessment and identifiying correlative biomarkers for predict therapeutic benefit. Finally, the potential of complementary combinatorial immunotherapeutic regimens is highly exciting and warrants expedited investigation. |*Immunotherapy [MESH] |Animals [MESH] |Glioblastoma/*immunology/*therapy [MESH]Immunotherapy advances for glioblastoma (epmc).pdf DeepDyve Pubget Overpricing