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10.1038/nri.2017.38 http://scihub22266oqcxt.onion/10.1038/nri.2017.38 C5532073!5532073 !28480895     free     free     free Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\28480895 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Nat+Rev+Immunol 2017 ; 17 (8 ): 483-494 Nephropedia Template TP {{tp|p=28480895 |t=2017. Immunological implications of pregnancy-induced microchimerism |pdf=|usr=}}{{28480895 }} gab.com Text Immunological implications of pregnancy-induced microchimerism JO: Nat Rev Immunol http://www.kidney.de/pget.php?&tw=1&pmid=28480895 #FOAvip Immunological identity is traditionally defined by genetically encoded antigens, with equal maternal and paternal contributions as a result of Mendelian inheritance. However, vertically transferred maternal cells also persist in individuals at very low levels throughout postnatal development. Reciprocally, mothers are seeded during pregnancy with genetically foreign fetal cells that persist long after parturition. Recent findings suggest that these microchimeric cells expressing non-inherited, familially relevant antigenic traits are not accidental 'souvenirs' of pregnancy, but are purposefully retained within mothers and their offspring to promote genetic fitness by improving the outcome of future pregnancies. In this Review, we discuss the immunological implications, benefits and potential consequences of individuals being constitutively chimeric with a biologically active 'microchiome' of genetically foreign cells. Twit Text FOAVip Immunological implications of pregnancy-induced microchimerism ????Nat Rev Immunol http://www.kidney.de/pget.php?&tw=1&pmid=28480895 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28480895 #FOAvip English Wikipedia <ref>{{Cite pmid|28480895 }}</ref> Immunological implications of pregnancy-induced microchimerism #MMPMID28480895 Kinder JM ; Stelzer IA ; Arck PC ; Way SS Nat Rev Immunol 2017[Aug]; 17 (8 ): 483-494 PMID28480895 show ga Immunological identity is traditionally defined by genetically encoded antigens, with equal maternal and paternal contributions as a result of Mendelian inheritance. However, vertically transferred maternal cells also persist in individuals at very low levels throughout postnatal development. Reciprocally, mothers are seeded during pregnancy with genetically foreign fetal cells that persist long after parturition. Recent findings suggest that these microchimeric cells expressing non-inherited, familially relevant antigenic traits are not accidental 'souvenirs' of pregnancy, but are purposefully retained within mothers and their offspring to promote genetic fitness by improving the outcome of future pregnancies. In this Review, we discuss the immunological implications, benefits and potential consequences of individuals being constitutively chimeric with a biologically active 'microchiome' of genetically foreign cells. |*Immune Tolerance [MESH] |*Maternal-Fetal Exchange [MESH] |Animals [MESH] |Autoimmunity [MESH] |Chimerism [MESH] |Female [MESH] |Fetus/cytology/immunology [MESH] |Humans [MESH] |Immune System/cytology [MESH] |Immunity, Maternally-Acquired [MESH] |Immunologic Memory [MESH] |Pregnancy/*immunology [MESH]Immunological implications of pregnancy-induced microchimerism (epmc).pdf DeepDyve Pubget Overpricing