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2014 ; 82
(6
): 1351-8
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Imaging techniques in spinal cord injury
#MMPMID23246741
Ellingson BM
; Salamon N
; Holly LT
World Neurosurg
2014[Dec]; 82
(6
): 1351-8
PMID23246741
show ga
BACKGROUND: Spinal imaging plays a critical role in the diagnosis, treatment, and
rehabilitation of patients with spinal cord injury (SCI). In recent years there
has been increasing interest in the development of advanced imaging techniques to
provide pertinent microstructural and metabolic information that is not provided
by conventional modalities. METHODS: This review details the pathophysiological
structural changes that accompany SCI, as well as their imaging correlates. The
potential clinical applications of novel spinal cord imaging techniques to SCI
are presented. RESULTS: There are a variety of novel advanced imaging techniques
that are principally focused on the microstructural and/or biochemical function
of the spinal cord, and can potentially be applied to traumatic SCI, including
diffusion tensor imaging, magnetic resonance spectroscopy, positron emission
tomography, single-photon emission computed tomography, and functional magnetic
resonance imaging. These techniques are presently in various stages of
development, including some whose applications are primarily limited to
laboratory investigation, whereas others are being actively used in clinical
practice. CONCLUSION: Advanced imaging of the spinal cord has tremendous
potential to provide patient-specific physiological information about the status
of cord integrity and health. Advanced spinal cord imaging is still at early
stages of development and clinical implementation but is likely to play an
increasingly important role in the management of spinal cord health in the
foreseeable future.