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2017 ; 4
(1
): 1-7
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Imaging of Renal Medullary Carcinoma
#MMPMID28405543
Greco F
; Faiella E
; Santucci D
; Mallio CA
; Nezzo M
; Quattrocchi CC
; Beomonte Zobel B
; Grasso RF
J Kidney Cancer VHL
2017[]; 4
(1
): 1-7
PMID28405543
show ga
Renal medullary carcinoma (RMC) is a rare, highly aggressive tumor recognized as
an independent pathological entity. African-descent adolescents and young adults
with sickle cell hemoglobinopathy are the most affected groups. This rare subtype
of renal cell carcinoma has its own morphogenetic and pathological
characteristics. The major clinical manifestations include gross hematuria,
abdominal or flank pain, and weight loss. The prognosis is very poor, with 95% of
cases diagnosed at an advanced stage of the disease. In this review, we summarize
the morphologic and dynamic characteristics of RMC under various imaging
modalities such as ultrasound, computed tomography, and magnetic resonance.
Differential diagnosis and management strategies are also discussed.