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2014 ; 20
(6
): 492-7
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Image-guided focal therapy for prostate cancer
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Sankineni S
; Wood BJ
; Rais-Bahrami S
; Walton Diaz A
; Hoang AN
; Pinto PA
; Choyke PL
; Türkbey B
Diagn Interv Radiol
2014[Nov]; 20
(6
): 492-7
PMID25205025
show ga
The adoption of routine prostate specific antigen screening has led to the
discovery of many small and low-grade prostate cancers which have a low
probability of causing mortality. These cancers, however, are often treated with
radical therapies resulting in long-term side effects. There has been increasing
interest in minimally invasive focal therapies to treat these tumors. While
imaging modalities have improved rapidly over the past decade, similar advances
in image-guided therapy are now starting to emerge--potentially achieving
equivalent oncologic efficacy while avoiding the side effects of conventional
radical surgery. The purpose of this article is to review the existing literature
regarding the basis of various focal therapy techniques such as cryotherapy,
microwave, laser, and high intensity focused ultrasound, and to discuss the
results of recent clinical trials that demonstrate early outcomes in patients
with prostate cancer.
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