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10.4274/tjh.2015.0335 http://scihub22266oqcxt.onion/10.4274/tjh.2015.0335 C5100728!5100728 !27211045     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=27211045 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\27211045 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Turk+J+Haematol 2016 ; 33 (2 ): 153-5 Nephropedia Template TP {{tp|p=27211045 |t=2016. ?diyopatik Trombositopenik Purpura Olgular?nda Düzenleyici T Hücreler |pdf=|usr=}}{{27211045 }} gab.com Text diyopatik Trombositopenik Purpura Olgular nda Düzenleyici T Hücreler JO: Turk J Haematol http://www.kidney.de/pget.php?&tw=1&pmid=27211045 #FOAvip OBJECTIVE: Immune thrombocytopenic purpura (ITP) is an immune-mediated bleeding disorder in which platelets are opsonized by autoantibodies and destroyed by an Fc receptor-mediated phagocytosis by the reticuloendothelial system within the spleen. Autoimmune processes are also considered in the pathogenesis of this disorder. CD4+CD25+FoxP3+ regulatory T (Treg) cells and CD8+CD28- Treg cells have roles in autoimmune diseases. We investigated these regulatory cells in ITP patients. MATERIALS AND METHODS: We included 22 ITP patients and 16 age-matched healthy subjects. CD4+CD25+FoxP3+ Treg cells and CD8+CD28- cells were investigated by three-color flow cytometry. The ratios of these cell populations to total lymphocytes were calculated. Statistical analysis was carried out with the Mann-Whitney U test. RESULTS: CD4+CD25+ Treg cells were 9.69±3.70% and 12.99±5.58% in patients with ITP and controls, respectively. CD4+CD25highFoxP3+ cells were 27.72±19.74% and 27.55±23.98% in ITP patients and controls, respectively. The percentages of both of these cell types were not statistically significant when compared to the control group. CONCLUSION: We did not find any differences in ratios of CD4+CD25+FoxP3+ Treg cells or CD8+CD28- T cells in lymphocytes between patients and healthy subjects. We conclude that these circulatory cells are not different in ITP, but further studies are needed to explore the putative roles of these regulatory cells. Twit Text FOAVip diyopatik Trombositopenik Purpura Olgular nda Düzenleyici T Hücreler ????Turk J Haematol http://www.kidney.de/pget.php?&tw=1&pmid=27211045 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27211045 #FOAvip English Wikipedia <ref>{{Cite pmid|27211045 }}</ref> ?diyopatik Trombositopenik Purpura Olgular?nda Düzenleyici T Hücreler #MMPMID27211045 Akyol Erikçi A ; Karagöz B ; Bilgi O Turk J Haematol 2016[Jun]; 33 (2 ): 153-5 PMID27211045 show ga OBJECTIVE: Immune thrombocytopenic purpura (ITP) is an immune-mediated bleeding disorder in which platelets are opsonized by autoantibodies and destroyed by an Fc receptor-mediated phagocytosis by the reticuloendothelial system within the spleen. Autoimmune processes are also considered in the pathogenesis of this disorder. CD4+CD25+FoxP3+ regulatory T (Treg) cells and CD8+CD28- Treg cells have roles in autoimmune diseases. We investigated these regulatory cells in ITP patients. MATERIALS AND METHODS: We included 22 ITP patients and 16 age-matched healthy subjects. CD4+CD25+FoxP3+ Treg cells and CD8+CD28- cells were investigated by three-color flow cytometry. The ratios of these cell populations to total lymphocytes were calculated. Statistical analysis was carried out with the Mann-Whitney U test. RESULTS: CD4+CD25+ Treg cells were 9.69±3.70% and 12.99±5.58% in patients with ITP and controls, respectively. CD4+CD25highFoxP3+ cells were 27.72±19.74% and 27.55±23.98% in ITP patients and controls, respectively. The percentages of both of these cell types were not statistically significant when compared to the control group. CONCLUSION: We did not find any differences in ratios of CD4+CD25+FoxP3+ Treg cells or CD8+CD28- T cells in lymphocytes between patients and healthy subjects. We conclude that these circulatory cells are not different in ITP, but further studies are needed to explore the putative roles of these regulatory cells. |Adult [MESH] |Biomarkers [MESH] |Case-Control Studies [MESH] |Female [MESH] |Flow Cytometry [MESH] |Humans [MESH] |Immunophenotyping [MESH] |Lymphocyte Count [MESH] |Lymphocyte Subsets/immunology/metabolism [MESH] |Male [MESH] |Middle Aged [MESH] |Phenotype [MESH] |Platelet Count [MESH] |Purpura, Thrombocytopenic, Idiopathic/*blood/*immunology [MESH] |T-Lymphocytes, Regulatory/*immunology/metabolism [MESH]?diyopatik Trombositopenik Purpura Olgular?nda Düzenleyici T Hücreler (epmc).pdf DeepDyve Pubget Overpricing