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2017 ; 40
(ä): 231-250
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Identifying Cellular and Molecular Mechanisms for Magnetosensation
#MMPMID28772099
Clites BL
; Pierce JT
Annu Rev Neurosci
2017[Jul]; 40
(ä): 231-250
PMID28772099
show ga
Diverse animals ranging from worms and insects to birds and turtles perform
impressive journeys using the magnetic field of the earth as a cue. Although
major cellular and molecular mechanisms for sensing mechanical and chemical cues
have been elucidated over the past three decades, the mechanisms that animals use
to sense magnetic fields remain largely mysterious. Here we survey progress on
the search for magnetosensory neurons and magnetosensitive molecules important
for animal behaviors. Emphasis is placed on magnetosensation in insects and
birds, as well as on the magnetosensitive neuron pair AFD in the nematode
Caenorhabditis elegans. We also review conventional criteria used to define
animal magnetoreceptors and suggest how approaches used to identify receptors for
other sensory modalities may be adapted for magnetoreceptors. Finally, we discuss
prospects for underutilized and novel approaches to identify the elusive
magnetoreceptors in animals.