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10.1080/2162402X.2015.1052935

http://scihub22266oqcxt.onion/10.1080/2162402X.2015.1052935
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C4635879!4635879 !26587329
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suck abstract from ncbi

pmid26587329       Oncoimmunology 2015 ; 4 (12 ): e1052935
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  • ISG15: A double edged sword in cancer #MMPMID26587329
  • Desai SD
  • Oncoimmunology 2015[Dec]; 4 (12 ): e1052935 PMID26587329 show ga
  • Interferon-Stimulated Gene 15 (ISG15) transcript is aberrantly expressed in most human malignancies, suggesting that it has a protumor function. However, at the protein level ISG15 has both protumor and immunomodulatory antitumor functions. Therapeutic strategies to maximize the latter may benefit cancer patients overexpressing the ISG15 pathway.
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