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2016 ; 2
(ä): 15
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Hypophysitis: Evaluation and Management
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Clin Diabetes Endocrinol
2016[]; 2
(ä): 15
PMID28702249
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Hypophysitis is the acute or chronic inflammation of the pituitary gland. The
spectrum of hypophysitis has expanded in recent years with the addition of two
histologic subtypes and recognition as a complication of treatment with immune
checkpoint inhibitors. Despite the increased number of published cases, the
pathogenesis of hypophysitis is poorly understood, and treatment strategies are
diverse and controversial. The diagnosis of hypophysitis generally requires
histopathologic confirmation. The presentation and clinical course of
hypophysitis varies. Hypophysitis can resolve spontaneously, relapse may occur,
and some cases can be refractory to treatment.