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10.2147/OTT.S119980

http://scihub22266oqcxt.onion/10.2147/OTT.S119980
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pmid27853381
      Onco+Targets+Ther 2016 ; 9 (ä): 6873-6884
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  • Hürthle cell carcinoma: current perspectives #MMPMID27853381
  • Ahmadi S ; Stang M ; Jiang XS ; Sosa JA
  • Onco Targets Ther 2016[]; 9 (ä): 6873-6884 PMID27853381 show ga
  • Hürthle cell carcinoma (HCC) can present either as a minimally invasive or as a widely invasive tumor. HCC generally has a more aggressive clinical behavior compared with the other differentiated thyroid cancers, and it is associated with a higher rate of distant metastases. Minimally invasive HCC demonstrates much less aggressive behavior; lesions <4 cm can be treated with thyroid lobectomy alone, and without radioactive iodine (RAI). HCC has been observed to be less iodine-avid compared with other differentiated thyroid cancers; however, recent data have demonstrated improved survival with RAI use in patients with HCC >2 cm and those with nodal and distant metastases. Patients with localized iodine-resistant disease who are not candidates for a wait-and-watch approach can be treated with localized therapies. Systemic therapy is reserved for patients with progressive, widely metastatic HCC.
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