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2015 ; 2
(1
): 86-104
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Human skin wetness perception: psychophysical and neurophysiological bases
#MMPMID27227008
Filingeri D
; Havenith G
Temperature (Austin)
2015[Jan]; 2
(1
): 86-104
PMID27227008
show ga
The ability to perceive thermal changes in the surrounding environment is
critical for survival. However, sensing temperature is not the only factor among
the cutaneous sensations to contribute to thermoregulatory responses in humans.
Sensing skin wetness (i.e. hygrosensation) is also critical both for behavioral
and autonomic adaptations. Although much has been done to define the biophysical
role of skin wetness in contributing to thermal homeostasis, little is known on
the neurophysiological mechanisms underpinning the ability to sense skin wetness.
Humans are not provided with skin humidity receptors (i.e., hygroreceptors) and
psychophysical studies have identified potential sensory cues (i.e. thermal and
mechanosensory) which could contribute to sensing wetness. Recently, a
neurophysiological model of human wetness sensitivity has been developed. In
helping clarifying the peripheral and central neural mechanisms involved in
sensing skin wetness, this model has provided evidence for the existence of a
specific human hygrosensation strategy, which is underpinned by perceptual
learning via sensory experience. Remarkably, this strategy seems to be shared by
other hygroreceptor-lacking animals. However, questions remain on whether these
sensory mechanisms are underpinned by specific neuromolecular pathways in humans.
Although the first study on human wetness perception dates back to more than
100 years, it is surprising that the neurophysiological bases of such an
important sensory feature have only recently started to be unveiled. Hence, to
provide an overview of the current knowledge on human hygrosensation, along with
potential directions for future research, this review will examine the
psychophysical and neurophysiological bases of human skin wetness perception.