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2018 ; 16
(2
): e2005358
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How the microbiome challenges our concept of self
#MMPMID29425197
Rees T
; Bosch T
; Douglas AE
PLoS Biol
2018[Feb]; 16
(2
): e2005358
PMID29425197
show ga
Today, the three classical biological explanations of the individual self--the
immune system, the brain, the genome--are being challenged by the new field of
microbiome research. Evidence shows that our resident microbes orchestrate the
adaptive immune system, influence the brain, and contribute more gene functions
than our own genome. The realization that humans are not individual, discrete
entities but rather the outcome of ever-changing interactions with microorganisms
has consequences beyond the biological disciplines. In particular, it calls into
question the assumption that distinctive human traits set us apart from all other
animals--and therefore also the traditional disciplinary divisions between the
arts and the sciences.