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2016 ; 8
(4
): a018036
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Horizontal Gene Transfer and the History of Life
#MMPMID26801681
Daubin V
; Szöll?si GJ
Cold Spring Harb Perspect Biol
2016[Apr]; 8
(4
): a018036
PMID26801681
show ga
Microbes acquire DNA from a variety of sources. The last decades, which have seen
the development of genome sequencing, have revealed that horizontal gene transfer
has been a major evolutionary force that has constantly reshaped genomes
throughout evolution. However, because the history of life must ultimately be
deduced from gene phylogenies, the lack of methods to account for horizontal gene
transfer has thrown into confusion the very concept of the tree of life. As a
result, many questions remain open, but emerging methodological developments
promise to use information conveyed by horizontal gene transfer that remains
unexploited today.