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2013 ; 8
(3
): 211-7
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Hodgkin lymphoma in pregnancy
#MMPMID23749243
Bachanova V
; Connors JM
Curr Hematol Malig Rep
2013[Sep]; 8
(3
): 211-7
PMID23749243
show ga
The peak incidence of Hodgkin lymphoma (HL) coincides with reproductive years,
and as many as 3 % of all HL patients present with concurrent pregnancy. The
management of a pregnant patient with HL requires a multidisciplinary approach
combining expertise in medical oncology, high-risk obstetrics, and neonatology,
as well as effective communication with the patient and her family. The goal is
to optimize the mother's chance of a cure while allowing for delivery of a
healthy child. A pregnant patient with HL should be staged by clinical
examination and judicious use of non-radiation imaging such as ultrasound,
balancing the need for accurate disease assessment with the need to minimize
invasive procedures. The treatment strategy is individualized to the symptoms,
lymphoma stage, gestational age and the patients' wishes. Therapeutic options
include treatment deferral or single-agent vinblastine with reservation of
multi-agent chemotherapy until the second or third trimester for the small
minority of patients with aggressive clinical presentation.
|Antineoplastic Combined Chemotherapy Protocols/administration &
dosage/therapeutic use
[MESH]