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2015 ; 13
(5
): 554-86
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English Wikipedia
Hodgkin lymphoma, version 2 2015
#MMPMID25964641
Hoppe RT
; Advani RH
; Ai WZ
; Ambinder RF
; Aoun P
; Bello CM
; Benitez CM
; Bierman PJ
; Blum KA
; Chen R
; Dabaja B
; Forero A
; Gordon LI
; Hernandez-Ilizaliturri FJ
; Hochberg EP
; Huang J
; Johnston PB
; Khan N
; Maloney DG
; Mauch PM
; Metzger M
; Moore JO
; Morgan D
; Moskowitz CH
; Mulroney C
; Poppe M
; Rabinovitch R
; Seropian S
; Tsien C
; Winter JN
; Yahalom J
; Burns JL
; Sundar H
J Natl Compr Canc Netw
2015[May]; 13
(5
): 554-86
PMID25964641
show ga
Hodgkin lymphoma (HL) is an uncommon malignancy involving lymph nodes and the
lymphatic system. Classical Hodgkin lymphoma (CHL) and nodular
lymphocyte-predominant Hodgkin lymphoma are the 2 main types of HL. CHL accounts
for most HL diagnosed in the Western countries. Chemotherapy or combined modality
therapy, followed by restaging with PET/CT to assess treatment response using the
Deauville criteria (5-point scale), is the standard initial treatment for
patients with newly diagnosed CHL. Brentuximab vedotin, a CD30-directed
antibody-drug conjugate, has produced encouraging results in the treatment of
relapsed or refractory disease. The potential long-term effects of treatment
remain an important consideration, and long-term follow-up is essential after
completion of treatment.