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1990 ; 43
(3
): 201-2
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Histopathology of acute human immunodeficiency virus exanthema
#MMPMID2332516
Balslev E
; Thomsen HK
; Weismann K
J Clin Pathol
1990[Mar]; 43
(3
): 201-2
PMID2332516
show ga
Acute exanthema occurs in patients who are human immunodeficiency virus (HIV)
positive before they become seropositive. The patients have influenza like
symptoms and a macular skin rash on the upper trunk. Histopathological
investigation of skin punch biopsy specimens from four patients with acute HIV
exanthema showed a normal epidermis and a sparse dermal, mainly perivascular,
lymphocytic/histiocytic infiltrate around vessels of the superficial plexus.
Histopathological changes of the exanthema of acute HIV infection are
non-specific and resemble those of other acute viral exanthema, but when both the
histopathological features and the clinical picture are suggestive, the clinician
should take into consideration the possibility of HIV infection.