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2016 ; 6
(ä): 26118
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High Resolution X-ray-Induced Acoustic Tomography
#MMPMID27189746
Xiang L
; Tang S
; Ahmad M
; Xing L
Sci Rep
2016[May]; 6
(ä): 26118
PMID27189746
show ga
Absorption based CT imaging has been an invaluable tool in medical diagnosis,
biology, and materials science. However, CT requires a large set of projection
data and high radiation dose to achieve superior image quality. In this letter,
we report a new imaging modality, X-ray Induced Acoustic Tomography (XACT), which
takes advantages of high sensitivity to X-ray absorption and high ultrasonic
resolution in a single modality. A single projection X-ray exposure is sufficient
to generate acoustic signals in 3D space because the X-ray generated acoustic
waves are of a spherical nature and propagate in all directions from their point
of generation. We demonstrate the successful reconstruction of gold fiducial
markers with a spatial resolution of about 350??m. XACT reveals a new imaging
mechanism and provides uncharted opportunities for structural determination with
X-ray.