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World J Hepatol
2015[Nov]; 7
(25
): 2603-9
PMID26557953
show ga
Hepatocellular adenomas (HCA) are rare benign liver tumors. Recent technological
advancements have helped in the early identification of such lesions. However,
precise diagnosis of hepatocellular incidentalomas remains challenging. Studies
at the molecular level have provided new insights into the genetics and
pathophysiology of these lesions. These in turn have raised questions over their
existing management modalities. However, the rarity of the tumor still restricts
the quality of evidence available for current recommendations and guidelines.
This article provides a comprehensive review on the etiology, molecular biology,
patho-physiology, clinical manifestations, and complications associated with HCA.
It also elaborates on the genetic advancements, existing diagnostic tools and
current guidelines for management for such lesions.
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