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10.3748/wjg.v21.i42.11887 http://scihub22266oqcxt.onion/10.3748/wjg.v21.i42.11887 C4641110!4641110 !26576077     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=26576077 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26576077 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       World+J+Gastroenterol 2015 ; 21 (42 ): 11887-92 Nephropedia Template TP {{tp|p=26576077 |t=2015. Hepatic immune tolerance induced by hepatic stellate cells |pdf=|usr=}}{{26576077 }} gab.com Text Hepatic immune tolerance induced by hepatic stellate cells JO: World J Gastroenterol http://www.kidney.de/pget.php?&tw=1&pmid=26576077 #FOAvip The liver, which is a metabolic organ, plays a pivotal role in tolerance induction. Hepatic stellate cells (HpSCs), which are unique non-parenchymal cells, exert potent immunoregulatory activity during cotransplantation with allogeneic islets effectively protecting the islet allografts from rejection. Multiple mechanisms participate in the immune tolerance induced by HpSCs, including the marked expansion of myeloid-derived suppressor cells (MDSCs), attenuation of effector T cell functions and augmentation of regulatory T cells. HpSC conditioned MDSC-based immunotherapy has been conducted in mice with autoimmune disease and the results show that this technique may be promising. This article demonstrates how HpSCs orchestrate both innate immunity and adaptive immunity to build a negative network that leads to immune tolerance. Twit Text FOAVip Hepatic immune tolerance induced by hepatic stellate cells ????World J Gastroenterol http://www.kidney.de/pget.php?&tw=1&pmid=26576077 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26576077 #FOAvip English Wikipedia <ref>{{Cite pmid|26576077 }}</ref> Hepatic immune tolerance induced by hepatic stellate cells #MMPMID26576077 Hsieh CC ; Hung CH ; Lu L ; Qian S World J Gastroenterol 2015[Nov]; 21 (42 ): 11887-92 PMID26576077 show ga The liver, which is a metabolic organ, plays a pivotal role in tolerance induction. Hepatic stellate cells (HpSCs), which are unique non-parenchymal cells, exert potent immunoregulatory activity during cotransplantation with allogeneic islets effectively protecting the islet allografts from rejection. Multiple mechanisms participate in the immune tolerance induced by HpSCs, including the marked expansion of myeloid-derived suppressor cells (MDSCs), attenuation of effector T cell functions and augmentation of regulatory T cells. HpSC conditioned MDSC-based immunotherapy has been conducted in mice with autoimmune disease and the results show that this technique may be promising. This article demonstrates how HpSCs orchestrate both innate immunity and adaptive immunity to build a negative network that leads to immune tolerance. |*Immune Tolerance [MESH] |Adaptive Immunity [MESH] |Adoptive Transfer/methods [MESH] |Animals [MESH] |Cell Communication [MESH] |Graft Rejection/immunology/prevention & control [MESH] |Graft Survival [MESH] |Hepatic Stellate Cells/*immunology/metabolism/transplantation [MESH] |Humans [MESH] |Immunity, Innate [MESH] |Immunosuppressive Agents/therapeutic use [MESH] |Liver/*immunology/metabolism [MESH] |Organ Transplantation/adverse effects [MESH]Hepatic immune tolerance induced by hepatic stellate cells (epmc).pdf DeepDyve Pubget Overpricing