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http://scihub22266oqcxt.onion/ C5621583!5621583 !28979043     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=28979043 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\28979043 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       J+Extra+Corpor+Technol 2017 ; 49 (3 ): 192-197 Nephropedia Template TP {{tp|p=28979043 |t=2017. Heparin: Effects upon the Glycocalyx and Endothelial Cells |pdf=|usr=}}{{28979043 }} gab.com Text Heparin: Effects upon the Glycocalyx and Endothelial Cells JO: J Extra Corpor Technol http://www.kidney.de/pget.php?&tw=1&pmid=28979043 #FOAvip Unfractionated heparin (UFH) is the most widely used injectable medication in the United States. UFH is a poly-dispersed, relatively impure combination of many polysaccharides known as a glycosaminoglycan. It is used as the primary anticoagulant for heart surgery as well as for active treatment of deep venous thrombosis, vascular thrombosis, stroke, and many other potentially catastrophic clotting syndromes. Many perfusionists and cardiac team members know little of the biology of UFH other than its use for cardiopulmonary bypass. UFH is very similar to heparin sulfate, found on the surface of endothelial cells. Heparan sulfate protects endothelial surfaces from inflammatory attack and serves as a mechano-transducer for vascular shear. UFH and all glycosaminoglycans have far reaching pleotropic actions. This review elaborates on some of fascinating unique biology of these polysaccharides. Perhaps a number of the complex complications attributed to CPB are either caused by, or set up to occur by the complicated biology of UFH? Twit Text FOAVip Heparin: Effects upon the Glycocalyx and Endothelial Cells ????J Extra Corpor Technol http://www.kidney.de/pget.php?&tw=1&pmid=28979043 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28979043 #FOAvip English Wikipedia <ref>{{Cite pmid|28979043 }}</ref> Heparin: Effects upon the Glycocalyx and Endothelial Cells #MMPMID28979043 Spiess BD J Extra Corpor Technol 2017[Sep]; 49 (3 ): 192-197 PMID28979043 show ga Unfractionated heparin (UFH) is the most widely used injectable medication in the United States. UFH is a poly-dispersed, relatively impure combination of many polysaccharides known as a glycosaminoglycan. It is used as the primary anticoagulant for heart surgery as well as for active treatment of deep venous thrombosis, vascular thrombosis, stroke, and many other potentially catastrophic clotting syndromes. Many perfusionists and cardiac team members know little of the biology of UFH other than its use for cardiopulmonary bypass. UFH is very similar to heparin sulfate, found on the surface of endothelial cells. Heparan sulfate protects endothelial surfaces from inflammatory attack and serves as a mechano-transducer for vascular shear. UFH and all glycosaminoglycans have far reaching pleotropic actions. This review elaborates on some of fascinating unique biology of these polysaccharides. Perhaps a number of the complex complications attributed to CPB are either caused by, or set up to occur by the complicated biology of UFH? |Anticoagulants/pharmacology/therapeutic use [MESH] |Blood Coagulation/drug effects [MESH] |Cardiopulmonary Bypass [MESH] |Endothelial Cells/*drug effects/physiology [MESH] |Glycocalyx/*drug effects/metabolism [MESH] |Heparin/*pharmacology/therapeutic use [MESH] |Humans [MESH]Heparin: Effects upon the Glycocalyx and Endothelial Cells (epmc).pdf DeepDyve Pubget Overpricing