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2015 ; 4
(1
): 106-111
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Henoch-Schönlein purpura complicated with severe gastrointestinal bleeding
#MMPMID28509281
Yamazaki T
; Akimoto T
; Iwazu Y
; Sugase T
; Takeshima E
; Numata A
; Komada T
; Yoshizawa H
; Otani N
; Morishita Y
; Saito O
; Takemoto F
; Muto S
; Kusano E
; Nagata D
CEN Case Rep
2015[May]; 4
(1
): 106-111
PMID28509281
show ga
Bleeding from the gastrointestinal tract is one of the common determinants of
morbidity and mortality in the ordinary clinical setting. The gastrointestinal
involvement of Henoch-Schönlein purpura (HSP) has often been described as
self-limiting, with no long-term morbidity. In this report, we describe our
experience with a male HSP patient who presented with abdominal pain, loss of
appetite and deteriorated renal function associated with nephrotic syndrome.
Despite the use of aggressive immunomodulatory treatments, including
corticosteroids and plasmapheresis, he developed lethal gastrointestinal
hemorrhage. We believe that the accumulation of more experience with additional
cases similar to ours is mandatory for the establishment of optimal management
for HSP patients with severe gastrointestinal manifestations.