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10.1016/j.jneuroim.2020.577326

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suck abstract from ncbi


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pmid32683185
      J+Neuroimmunol 2020 ; 346 (ä): 577326
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  • Hemorrhagic encephalopathy associated with COVID-19 #MMPMID32683185
  • Krett JD ; Jewett GAE ; Elton-Lacasse C ; Fonseca K ; Hahn C ; Au S ; Koch MW
  • J Neuroimmunol 2020[Sep]; 346 (ä): 577326 PMID32683185 show ga
  • The mechanisms for neurological complications of COVID-19, the disease caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), are not yet well understood. We present a critically ill man with a COVID-19-associated hemorrhagic encephalopathy. SARS-CoV-2 RNA was not detected in cerebrospinal fluid (CSF) or blood. CSF analyses suggested dysregulation of pro-inflammatory cytokine pathways, particularly tumor necrosis factor-? and interleukin-6, consistent with a cytokine release syndrome. The patient gradually recovered with supportive care and neurological rehabilitation. Awareness of this clinical entity may facilitate the identification of patients with a potentially remediable cause of encephalopathy in COVID-19.
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