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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 J+Med+Life
2017 ; 10
(2
): 112-117
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Helicobacter pylori infection: old and new
#MMPMID28616085
Diaconu S
; Predescu A
; Moldoveanu A
; Pop CS
; Fierbin?eanu-Braticevici C
J Med Life
2017[Apr]; 10
(2
): 112-117
PMID28616085
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Helicobacter pylori is a spiral-shaped bacterium that grows in the digestive
tract and may be present in more than half of the world's population. The
clinical features of Helicobacter pylori range from asymptomatic gastritis to
gastrointestinal malignancy. Mucosa-associated lymphoid tissue (MALT) lymphoma is
a low-grade B-cell marginal zone lymphoma and Helicobacter pylori has been
detected in more than 75% of the patients with MALT lymphoma. Many tests for the
detection of Helicobacter pylori are available, including antibody tests, urea
breath tests, stool antigen tests and endoscopic biopsies. The eradication of
Helicobacter pylori usually prevents the return of ulcers and ulcer complications
even after appropriate medications such as PPIs are stopped. The eradication of
Helicobacter pylori is important in the treatment of the rare condition of the
stomach known as MALT lymphoma. The treatment of Helicobacter pylori to prevent
stomach cancer is controversial. Confirmation of eradication is recommended in
associated ulcers, persistent dyspepsia despite a test-and-treat approach, MALT
lymphoma, and previous treatment for early-stage gastric cancer. The urea breath
test and stool antigen test can be used to confirm the eradication and should be
performed at least 4 weeks after the completion of therapy. Several diseases have
been reported to be associated with Helicobacter pylori infection, including
hematologic diseases, such as ITP, idiopathic iron deficiency anemia and vitamin
B12 deficiency. There is a positive trend in the association between Helicobacter
pylori infection and neurodegenerative disorders and new data showed a reduced
risk of death due to stroke and lung cancer but an increased risk of preeclampsia
in infected women, which requires further investigations.
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