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10.1016/j.ydbio.2015.01.019 http://scihub22266oqcxt.onion/10.1016/j.ydbio.2015.01.019 C4361250!4361250 !25641695     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=25641695 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\25641695 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Dev+Biol 2015 ; 400 (1 ): 94-104 Nephropedia Template TP {{tp|p=25641695 |t=2015. Hedgehog signaling in prostate epithelial-mesenchymal growth regulation |pdf=|usr=}}{{25641695 }} gab.com Text Hedgehog signaling in prostate epithelial-mesenchymal growth regulation JO: Dev Biol http://www.kidney.de/pget.php?&tw=1&pmid=25641695 #FOAvip The prostate gland plays an important role in male reproduction, and is also an organ prone to diseases such as benign prostatic hyperplasia (BPH) and prostate cancer. The prostate consists of ducts with an inner layer of epithelium surrounded by stroma. Reciprocal signaling between these two cell compartments is instrumental to normal prostatic development, homeostasis, regeneration, as well as tumor formation. Hedgehog (HH) signaling is a master regulator in numerous developmental processes. In many organs, HH plays a key role in epithelial-mesenchymal signaling that regulates organ growth and tissue differentiation, and abnormal HH signaling has been implicated in the progression of various epithelial carcinomas. In this review, we focus on recent studies exploring the multipotency of endogenous postnatal and adult epithelial and stromal stem cells and studies addressing the role of HH in prostate development and cancer. We discuss the implications of the results for a new understanding of prostate development and disease. Insight into the cellular and molecular mechanisms underlying epithelial-mesenchymal growth regulation should provide a basis for devising innovative therapies to combat diseases of the prostate. Twit Text FOAVip Hedgehog signaling in prostate epithelial-mesenchymal growth regulation ????Dev Biol http://www.kidney.de/pget.php?&tw=1&pmid=25641695 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25641695 #FOAvip English Wikipedia <ref>{{Cite pmid|25641695 }}</ref> Hedgehog signaling in prostate epithelial-mesenchymal growth regulation #MMPMID25641695 Peng YC ; Joyner AL Dev Biol 2015[Apr]; 400 (1 ): 94-104 PMID25641695 show ga The prostate gland plays an important role in male reproduction, and is also an organ prone to diseases such as benign prostatic hyperplasia (BPH) and prostate cancer. The prostate consists of ducts with an inner layer of epithelium surrounded by stroma. Reciprocal signaling between these two cell compartments is instrumental to normal prostatic development, homeostasis, regeneration, as well as tumor formation. Hedgehog (HH) signaling is a master regulator in numerous developmental processes. In many organs, HH plays a key role in epithelial-mesenchymal signaling that regulates organ growth and tissue differentiation, and abnormal HH signaling has been implicated in the progression of various epithelial carcinomas. In this review, we focus on recent studies exploring the multipotency of endogenous postnatal and adult epithelial and stromal stem cells and studies addressing the role of HH in prostate development and cancer. We discuss the implications of the results for a new understanding of prostate development and disease. Insight into the cellular and molecular mechanisms underlying epithelial-mesenchymal growth regulation should provide a basis for devising innovative therapies to combat diseases of the prostate. |Adult Stem Cells/*metabolism [MESH] |Animals [MESH] |Epithelial-Mesenchymal Transition/*physiology [MESH] |Gene Expression Regulation, Developmental/*physiology [MESH] |Hedgehog Proteins/*metabolism [MESH] |Humans [MESH] |Male [MESH] |Mice [MESH] |Prostate/*embryology/*growth & development/metabolism [MESH] |Prostatic Neoplasms/metabolism/*physiopathology [MESH] |Signal Transduction/*physiology [MESH]Hedgehog signaling in prostate epithelial-mesenchymal growth regulatio(epmc).pdf DeepDyve Pubget Overpricing