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10.1093/database/bau112 http://scihub22266oqcxt.onion/10.1093/database/bau112 C5630898!5630898 !25502817     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\25502817 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Database+(Oxford) 2014 ; 2014 (ä): bau112 Nephropedia Template TP {{tp|p=25502817 |t=2014. HGV&TB: a comprehensive online resource on human genes and genetic variants associated with tuberculosis |pdf=|usr=}}{{25502817 }} gab.com Text HGV&TB: a comprehensive online resource on human genes and genetic variants associated with tuberculosis JO: Database (Oxford) http://www.kidney.de/pget.php?&tw=1&pmid=25502817 #FOAvip Tuberculosis (TB) is an infectious disease caused by fastidious pathogen Mycobacterium tuberculosis. TB has emerged as one of the major causes of mortality in the developing world. Role of host genetic factors that modulate disease susceptibility have not been studied widely. Recent studies have reported few genetic loci that provide impetus to this area of research. The availability of tools has enabled genome-wide scans for disease susceptibility loci associated with infectious diseases. Till now, information on human genetic variations and their associated genes that modulate TB susceptibility have not been systematically compiled. In this work, we have created a resource: HGV&TB, which hosts genetic variations reported to be associated with TB susceptibility in humans. It currently houses information on 307 variations in 98 genes. In total, 101 of these variations are exonic, whereas 78 fall in intronic regions. We also analysed the pathogenicity of the genetic variations, their phenotypic consequences and ethnic origin. Using various computational analyses, 30 variations of the 101 exonic variations were predicted to be pathogenic. The resource is freely available at http://genome.igib.res.in/hgvtb/index.html. Using integrative analysis, we have shown that the disease associated variants are selectively enriched in the immune signalling pathways which are crucial in the pathophysiology of TB. Database URL: http://genome.igib.res.in/hgvtb/index.html Twit Text FOAVip HGV&TB: a comprehensive online resource on human genes and genetic variants associated with tuberculosis ????Database (Oxford) http://www.kidney.de/pget.php?&tw=1&pmid=25502817 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25502817 #FOAvip English Wikipedia <ref>{{Cite pmid|25502817 }}</ref> HGV&TB: a comprehensive online resource on human genes and genetic variants associated with tuberculosis #MMPMID25502817 Sahajpal R ; Kandoi G ; Dhiman H ; Raj S ; Scaria V ; Bhartiya D ; Hasija Y Database (Oxford) 2014[]; 2014 (ä): bau112 PMID25502817 show ga Tuberculosis (TB) is an infectious disease caused by fastidious pathogen Mycobacterium tuberculosis. TB has emerged as one of the major causes of mortality in the developing world. Role of host genetic factors that modulate disease susceptibility have not been studied widely. Recent studies have reported few genetic loci that provide impetus to this area of research. The availability of tools has enabled genome-wide scans for disease susceptibility loci associated with infectious diseases. Till now, information on human genetic variations and their associated genes that modulate TB susceptibility have not been systematically compiled. In this work, we have created a resource: HGV&TB, which hosts genetic variations reported to be associated with TB susceptibility in humans. It currently houses information on 307 variations in 98 genes. In total, 101 of these variations are exonic, whereas 78 fall in intronic regions. We also analysed the pathogenicity of the genetic variations, their phenotypic consequences and ethnic origin. Using various computational analyses, 30 variations of the 101 exonic variations were predicted to be pathogenic. The resource is freely available at http://genome.igib.res.in/hgvtb/index.html. Using integrative analysis, we have shown that the disease associated variants are selectively enriched in the immune signalling pathways which are crucial in the pathophysiology of TB. Database URL: http://genome.igib.res.in/hgvtb/index.html |*Genetic Predisposition to Disease [MESH] |*Genetic Variation [MESH] |*Internet [MESH] |Chromosome Mapping [MESH] |Databases, Genetic [MESH] |Genetic Loci [MESH] |Genetics, Population [MESH] |Genome, Human/genetics [MESH] |Humans [MESH] |Phenotype [MESH] |Quantitative Trait, Heritable [MESH] |Software [MESH]HGV&TB: a comprehensive online resource on human genes and genetic var(epmc).pdf DeepDyve Pubget Overpricing