Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\27625997
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Front+Cell+Infect+Microbiol
2016 ; 6
(ä): 95
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Gut Microbiota: A Contributing Factor to Obesity
#MMPMID27625997
Harakeh SM
; Khan I
; Kumosani T
; Barbour E
; Almasaudi SB
; Bahijri SM
; Alfadul SM
; Ajabnoor GM
; Azhar EI
Front Cell Infect Microbiol
2016[]; 6
(ä): 95
PMID27625997
show ga
Obesity, a global epidemic of the modern era, is a risk factor for cardiovascular
diseases (CVD) and diabetes. The pervasiveness of obesity and overweight in both
developed as well as developing populations is on the rise and placing a huge
burden on health and economic resources. Consequently, research to control this
emerging epidemic is of utmost importance. Recently, host interactions with their
resident gut microbiota (GM) have been reported to be involved in the
pathogenesis of many metabolic diseases, including obesity, diabetes, and CVD.
Around 10(14) microorganisms reside within the lower human intestine and many of
these 10(14) microorganisms have developed mutualistic or commensal associations
with the host and actively involved in many physiological processes of the host.
However, dysbiosis (altered gut microbial composition) with other predisposing
genetic and environmental factors, may contribute to host metabolic disorders
resulting in many ailments. Therefore, delineating the role of GM as a
contributing factor to obesity is the main objective of this review. Obesity
research, as a field is expanding rapidly due to major advances in nutrigenomics,
metabolomics, RNA silencing, epigenetics, and other disciplines that may result
in the emergence of new technologies and methods to better interpret causal
relationships between microbiota and obesity.
free
free
free
