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2017 ; 2017
(ä): 6501738
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Granulomatosis with Polyangiitis with Myocarditis and Ventricular Tachycardia
#MMPMID28912820
Hanna RM
; Lopez E
; Wilson J
Case Rep Med
2017[]; 2017
(ä): 6501738
PMID28912820
show ga
Granulomatosis with polyangiitis (GPA), previously known as Wegener's
granulomatosis, is a pulmonary-renal syndrome affecting small and medium sized
blood vessels. The disease has a prevalence in studies ranging from 3 to 15.7
cases per 100,000, with a noted increasing incidence and prevalence in more
recent studies. Pulmonary manifestations include hemorrhage, lung cavitary
lesions, and pulmonary fibrosis. Within the kidney, GPA is known to cause rapidly
progressive pauci-immune crescentic glomerulonephritis. Rare and severe
cardiovascular manifestations include pericarditis, arrhythmias, myocarditis, and
aortic valve disease. Our patient is a 43-year-old female with typical pulmonary
and renal lesions from GPA and also acute myocarditis, multiple episodes of
ventricular tachycardia, and a severe reactive thrombocytosis.