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2018 ; 33
(6
): 947-955
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Graft nephrectomy in children
#MMPMID28631039
Phillips BL
; Callaghan CJ
Pediatr Nephrol
2018[Jun]; 33
(6
): 947-955
PMID28631039
show ga
Kidney transplantation is recognised as the gold standard treatment of end-stage
renal disease in most children, with excellent graft survival rates. When graft
failure occurs, renal transplant recipients (RTRs) have the option of removal of
the transplant (graft nephrectomy [GN]), or leaving the failed transplant in
situ. The aims of this review are to discuss the indications for GN, surgical
techniques, outcomes after GN (including risks of allosensitisation and the
impact on subsequent transplants), and the possible role of routine GN in the
asymptomatic RTR with a failed renal allograft. Literature in both the pediatric
and adult renal transplant fields is reviewed. We also discuss how future
research in this area could advance our knowledge of which patients to select for
GN, and the most appropriate surgical approach.