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2018 ; 11
(ä): 219-229
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Genitogluteal porokeratosis: a clinical review
#MMPMID29750048
Joshi R
; Minni K
Clin Cosmet Investig Dermatol
2018[]; 11
(ä): 219-229
PMID29750048
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Porokeratosis is an uncommon disorder of keratinization that presents with
keratotic papules or annular plaques that expand centrifugally with a thread-like
elevated border. A distinctive histologic structure, the cornoid lamella, is
diagnostic of this disorder and consists of a column of parakeratosis with the
absence of the granular layer and dyskeratotic cells in the upper spinous zone.
Porokeratosis confined to the genitogluteal region is rare and may be
subclassified into three types, namely, classical porokeratosis on the genital
region, ptychotropic porokeratosis most often seen in the natal cleft and
buttocks and penoscrotal porokeratosis that is seen on the penis and adjacent
scrotal skin in young men in their third decade of life. Genitogluteal
porokeratosis is usually pruritic and may be undiagnosed for several years as it
does not resemble classical porokeratosis in many cases; however, a biopsy is
diagnostic. In general, response of genital porokeratosis to any modality of
treatment is disappointing. No malignant changes have hereto been reported in
porokeratosis restricted to the genitogluteal region.
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