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10.1126/science.aaa8954 http://scihub22266oqcxt.onion/10.1126/science.aaa8954 C4694563!4694563 !26404826     free     free     free Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26404826 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Science 2015 ; 349 (6255 ): 1489-94 Nephropedia Template TP {{tp|p=26404826 |t=2015. Genetics and genomics of psychiatric disease |pdf=|usr=}}{{26404826 }} gab.com Text Genetics and genomics of psychiatric disease JO: Science http://www.kidney.de/pget.php?&tw=1&pmid=26404826 #FOAvip Large-scale genomic investigations have just begun to illuminate the molecular genetic contributions to major psychiatric illnesses, ranging from small-effect-size common variants to larger-effect-size rare mutations. The findings provide causal anchors from which to understand their neurobiological basis. Although these studies represent enormous success, they highlight major challenges reflected in the heterogeneity and polygenicity of all of these conditions and the difficulty of connecting multiple levels of molecular, cellular, and circuit functions to complex human behavior. Nevertheless, these advances place us on the threshold of a new frontier in the pathophysiological understanding, diagnosis, and treatment of psychiatric disease. Twit Text FOAVip Genetics and genomics of psychiatric disease ????Science http://www.kidney.de/pget.php?&tw=1&pmid=26404826 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26404826 #FOAvip English Wikipedia <ref>{{Cite pmid|26404826 }}</ref> Genetics and genomics of psychiatric disease #MMPMID26404826 Geschwind DH ; Flint J Science 2015[Sep]; 349 (6255 ): 1489-94 PMID26404826 show ga Large-scale genomic investigations have just begun to illuminate the molecular genetic contributions to major psychiatric illnesses, ranging from small-effect-size common variants to larger-effect-size rare mutations. The findings provide causal anchors from which to understand their neurobiological basis. Although these studies represent enormous success, they highlight major challenges reflected in the heterogeneity and polygenicity of all of these conditions and the difficulty of connecting multiple levels of molecular, cellular, and circuit functions to complex human behavior. Nevertheless, these advances place us on the threshold of a new frontier in the pathophysiological understanding, diagnosis, and treatment of psychiatric disease. |*Mutation [MESH] |DNA Mutational Analysis [MESH] |Genetic Heterogeneity [MESH] |Genomics [MESH] |Humans [MESH] |Mental Disorders/classification/*diagnosis/*genetics [MESH] |Models, Genetic [MESH]Genetics and genomics of psychiatric disease (epmc).pdf DeepDyve Pubget Overpricing